2 Acknowledgements The National Interoperability Collaborative (NIC) Opioid Use Disorder Prevention Playbook was researched and written by Paul Wormeli, a member of the Stewards of Change Institute (SOCI) Board of Directors. It was edited by Adam Pertman, an SOCI senior consultant and NIC’s Coordination and Communications Director. NIC is an initiative of SOCI. This NIC playbook addresses the most-significant public health emergency in modern U.S. history by focusing on an aspect of the epidemic that we believe has received far too little attention: prevention. This collection of ideas, approaches and strategies – or plays – is derived from the growing number of efforts by practitioners, researchers and policy-makers around the country to “get upstream” of this national crisis, in addition to providing treatment and saving lives. The feedback from reviewers of earlier drafts of this document has been invaluable in shaping this collection of plays, which we hope will not only focus greater national attention on prevention, but also will provide guidance on specific actions that communities, jurisdictions, governments and organizations can take toward prioritizing that end. We acknowledge and appreciate the constructive contributions to this playbook from the following: Melinda Baldwin, PhD, Child Welfare Department Specialist at the Administration for Children and Families, U.S. Department of Health and Human Services Mannone A. Butler, Esq, Executive Director of the Criminal Justice Coordinating Council Kate Garvey, Director of the Department of Community and Human Services of Alexandria, VA Fran Gerbig, MPH, OCPC, Assistant Executive Director of Prevention Action Alliance Sean Gunderson, Co-Founder of iTether Technologies Inc. William Hazel, MD, Senior Advisor for Strategic Initiatives and Policy at George Mason University; former Secretary of Health and Human Resources for the Commonwealth of Virginia; and member of the Board of Directors of the Stewards of Change Institute Linda Hill, Director of the Archer Group and former Executive Director of Stafford Junction Bryant Thomas Karras, MD, Chief Public Health Informatics Officer, Washington State Department of Health; founding member of the International Society for Disease Surveillance Anna Lembke, MD, Associate Professor and Medical Director of Addiction Medicine, Stanford University School of Medicine; Program Director of the Stanford Addiction Medicine Fellowship; and Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic Robert May, Assistant Director of Program Services at the IJIS Institute Tanya L. Stauffer, Practice Director at Analysts International Corporation and Board Member at the IJIS Institute Chris Traver,SeniorAdvisorforInformationSharingattheOfficeofPlanning,ResearchandEvaluation,Administration for Children and Families, U.S. Department of Health and Human Services We also sincerely thank the Kresge Foundation for providing the funding and vision that enabled the Stewards of Change Institute and its leadership partner, AcademyHealth, to create NIC. In addition, we are very grateful to IBM, Microsoft and the Annie E. Casey Foundation for their support in launching NIC. Finally, we extend our deep appreciation to all of the passionate people throughout the United States who are working every day to combat the devastating opioid epidemic. Sincerely, Daniel Stein, Co-Principal Investigator of NIC President, Stewards of Change Institute